Top 15 Humorous Comedy Anime on Amazon Prime Video US (Updated)

Amazon Prime Video is an online streaming-video service that offers a selection of TV shows, movies, and anime. Research has been done which unveils that more than 112 million US citizens are Amazon Prime subscribers. Therefore, we are here with another list of Top 15 Humorous Comedy Anime on Amazon Prime Video US.

The anime industry has seen some significant changes in the last few years due to the rise of streaming services like Crunchyroll, Netflix, and Amazon Prime Video. These new providers contribute an immense amount of content for reasonable prices. In the list, we have done the ranking of the funniest anime based on the “myanimelist” score. So, without any further ado, let’s begin.

Top 15 Humorous Comedy Anime on Amazon Prime Video US

15. Kiss Him, Not Me – 7.04

Kiss Him, Not Me

Kiss Him, Not Me” is a comedy romance anime with Shoujo demographics. It has a total number of 12 episodes, and all are available on Amazon Prime Video US. The plot spins around a second-year high school girl, Kae Serinuma, who is lovely but chubby. She is an Otaku and fond of Boy’s love. One day, in an anime series, her favorite character passed away.

She became depressed and locked herself in a room for an entire week. The result of depression and skipping meals leads to losing a large amount of weight. Now she has become the prettiest girl in her class. She finds herself at the center of the attention of four boys. They all desire to spend time with her, but she (BL-obsessed) wants them to love each other.



Isekai Quartet is a comedy parody anime series with two seasons available on Amazon Prime Video US. This anime is best for any age group.

It’s a parody of different anime series where we witness deranged military girl Tanya Degurechaff, an isekai protagonist Satou Kazuma, an expansionist Ainz Ooal Gown, and demon sisters Rem and Ram in the same classroom.

The best part is they all have become chibis and have to attend school in an unfamiliar world. Also, this anime series will never be boring.

13. My Bride is a Mermaid – 7.71

My Bride is a Mermaid anime

Seto no Hanayome or My Bride is a Mermaid is an another school romance comedy anime on the list. It has only 26 episodes. It is also one of the funniest anime on Amazon Prime.

The fantasy plot revolves around a middle school boy, Nagasumi Michishio, who travels to the Seto island during his summer vacation.

While swimming at Mio Sun Beach, he got cramps, and no one was there to help him. After losing his consciousness, a mermaid saves his life, and the same night they meet.

Her name is Sun Seto, and she is a mermaid from a Yakuza family. However, things get change when Nagasumi knows that he has to marry to save her life from execution because her identity is revealed in front of a human.

12. That Time I Got Reincarnated as a Slime – 8.12

That Time I Got Reincarnated as a Slime anime

Maximum of you know about this anime series. It is also one of the best comedy anime on Amazon Prime Video US. The excellent news is Prime has all three seasons of this series. Therefore, you can commence this series now.

The story begins with Satoru Mikami, thirty-seven years old cooperate worker who is living a boring life. Unfortunately, one day he is stabbed by some colleagues. During the last phase of his life, he hears some unusual echoes.

When he regains his consciousness, he discovers himself in an unfamiliar world and in a Slime body. Now he has an ability to devour anything and mimic its appearance. And from there, his new journey begins. It is an action anime series with a lot of comedy in it.

11. Toradora! – 8.14

Toradora! anime

Toradora is one of my favorite funny anime drama with a slice of life in it. It is also a school romance anime. I highly recommend you to watch this anime.

It is a story of a gentle boy, Ryuuji Takasu, and a short cute fragile girl, Taiga Aisaka, who accidentally meet. Taiga is known as the “Palmtop Tiger” because of her feisty personality.

One day, Ryuuji discovers that Taiga has a crush on Yuusaku Kitamura, who is his best friend. Therefore, to take this opportunity as his chance, Ryuuji reveals that he has a crush on Minori Kushieda, who is Taiga Aisaka’s best friend. In this, they both have to work together to fulfill their dreams.

10. Hinamatsuri – 8.18

Hinamatsuri anime

Hinamatsuri is a supernatural comedy series with a Seinen demographics. It is an excellent funny anime on Amazon Prime with a slice of life in it. It has a total of 12 episodes, so if you want a short comedy anime with a good plot, then this drama is for you.

It has an exciting plot where Yoshifumi Nitta, a yakuza member who is living a great life, suddenly encounters a capsule. Inside a capsule, he found a young girl, Hina, who possesses psychic powers.

But the twist is when she has to use her power to order to maintain otherwise, she loses control. From there, the life of Nitta has changed.

9. Fruits Basket – 8.22

Fruits Basket anime

Fruits Basket is the most popular anime series with Comedy, Drama, Romance, Slice of Life, and Supernatural as its genres. It has a total of 3 seasons, and you can watch it all on Amazon Prime. In contrast, it is a complete anime with slice of life.

The story begins when a beautiful girl, Tohru is forced to live in a tent after a sudden tragedy happens to her family. She is fond of the Chinese Zodiacs. Living in a harsh condition, she discovers that her tent is an illegal possession residing on the private property of the Sohma family.

Tohru is a hardworking girl. One day she encounters Shigure and Yuki, the Sohma brothers, in her school. Soon they both find out that she lives in a tent.

They invite her to their residence, where she discovers that the Sohma family has a cursed secret that turns them into Chinese Zodiac’s animals whenever they are hugged by the opposite gender.

8. Daily Life of High School Boys – 8.25

Daily Life of High School Boys anime

Another comedy anime with a slice of life to which you all can relate from your old school days. The story revolves around three boys of the Sanada North High School, Hidenori, Yoshitake, and Tadakuni. Every time they are all busy in their colorful imaginations of robots, love, and drama.

In contrast, they are just ordinary trio who are trying to pass their time with fantasy discussion. But things get change when one evening they have an unexpected romantic encounter on the riverbank.

7. Grand Blue Dreaming – 8.42

Grand Blue dreaming anime

Grand Blue Dreaming is a slice-of-life comedy anime that is a dream of every Otaku. This is also a must-watch anime with a total of 12 episodes available on Amazon Prime. It is a story of a college boy, Iori Kitahara, who decides to take residence near his uncle’s scuba diving shop, Grand Blue.

But his life makes a sudden twist when he meets members of the Diving Club who are enjoying their life to the fullest. Now, Iori has decided to be a part of this group. So, how will his dream change?

6. Nichijou – My Ordinary Life – 8.46

Nichijou - My Ordinary Life anime

Nichijou is a Shounen school comedy anime for all age groups. It has a total of 26 episodes and is one of the best comedy anime, especially for kids on Amazon Prime Video US.

The story primarily focuses on three high school girls, Mio Naganohara, Yuuko Aioi, and Mai Minakami. Later on, they meet a genius boy of the same age, Hakase Shinonome, her robot caretaker Nano, and their talking cat Sakamoto.

Now all six experience a normal life with some exciting twists every day. The anime is full of childish comedy, which you’ll definitely enjoy.

5. The Disastrous Life of Saiki K. – 8.43

The Disastrous Life of Saiki K. anime

The Disastrous Life of Saiki K. is a popular supernatural anime with a lot of comedy in it. It is a story where psychic abilities are a curse rather than a blessing for Kusuo Saiki. He is also considered to be one of the strongest anime characters in the anime world, having every supernatural ability.

However, Kusuo Saiki wants a normal life like an ordinary person. But his crazy friends always end up in some trouble. Later on, Kusuo discovers that his dream of living everyday life is not going to be easy.

4. One Punch Man – 8.52

One Punch Man Anime

One Punch Man is the second most popular anime series on this list. If you have too much action with comedy scenes, then this series is best for you. Currently, only two seasons are there and both of them are available on Amazon Prime.

It is a story of an ordinary man, Saitama, who desires to be a Hero. Heroes are the extraordinary humans with abilities who protect humanity from monsters/villains. To achieve his desires, he trains 100 push-ups, 100 sit-ups, 100 squats, and 10 km run every day for three years.

By overdoing his training, he accidentally removes his limiter, due to which he has become one of the strongest anime characters. Now he feels bored because no one in the entire universe is strong enough to give him a fight.

3. Kaguya-sama: Love is War – 8.66

Kaguya-sama: Love is War

Kaguya-sama: Love is War is a Seinen comedy anime series with a psychological romance in it. Presently, only 2nd season is available on Amazon Prime. For the 1st season, you’ve to visit another platform.

The plot focuses on Shuchiin Academy, where both Miyuki Shirogane and Kaguya Shinomiya are the top representatives of the student councils and are from the wealthiest families.

They both have feelings for each other; however, they fear to confess first because of the ideology that if they get rejected, they will be considered the lesser.

2. GTO Great Teacher Onizuka – 8.69

GTO Great Teacher Onizuka Anime

Great Teacher Onizuka is one of the most underrated Shounen anime. It has comedy, drama, and slice of life in its 43 episodes. Luckily, it is available on US Amazon Prime. It also has a fantastic plot.

A twenty-two years old ex-bike gang leader, Eikichi Onizuka, has a dream to become the most outstanding high school teacher so that he can get a loving teenage wife. He is a pervert guy with a lot of greed and laziness.

One day he gets a job as a homeroom teacher of Class 3-4, where we know that he is not an average pervert teacher. He is a man who is ready to take any challenge.

In schools, bullying, suicide, and sexual harassments are common issues. Onizuka decides to take action against the root causes of these problems.

1. Gintama – 9.09


Gintama is the most popular parody anime on this list. If you are an Otaku who loves comedy anime, then you’ve to watch Gintama. Unfortunately, only Season 3 & 4 are available on Amazon Prime right now.

The sci-fi story revolves around an environment where aliens have conquered Japan and banned the samurais and swords. Gintoki, Shinpachi, and Kagura are the broke members of the Yorozuya team who do any type of work to earn money.

One night, an alien ship crashed just before Gintoki’s house. An injured member of the crew gives Gintoki a strange clock shape powerful device and warns him not to use it. However, he set this device as his alarm clock, and in the morning, after smashing the device, he and his friends’ lives changed.

Here, we conclude our list of Top 15 Humorous Comedy Anime on Amazon Prime Video US 2021 Ranked. I hope you like it all. To watch, the user should have a Prime subscription to Amazon.

If not, then he/she can proceed to watch these anime on different paid platforms like Crunchyroll, VRV, etc. We will be back with another ranking article with Prime availability. Till then, stay tuned with us.

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